Informed by the results of our initial survey, the sIRB Alliance at NYU School of Medicine invited individuals from Clinical and Translational Science Award (CTSA) and non-CTSA institutions to address relevant local context issues in a series of working group teleconferences.

The working groups characterized a range of acceptable practices that may be considered for adoption as best practices in several areas. Over 100 sites contributed to these documents and consensus and the final solutions, all of which can be found below. We encourage sIRBs and research teams to begin using these standardized best practices when submitting to sIRBs reviewing National Institutes of Health–funded research. Please let us know what you think by contacting us at helen.panageas@nyulangone.org.

• Consensus Survey Results and Information

• Addendum to SMART IRB Agreement

• Ancillary Review Committees

• Data Safety Monitoring Plan Charter

• Recruitment Materials

• Reportable New Information

• Research Participant Biomedical Informed Consent Form

• Research Participant Non-Biomedical Informed Consent Form

• Review of Financial Conflicts of Interest

• Study Team Training and Qualifications

• Vulnerable Populations